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Topamax / Topiramate

Brand: Topamax
Generic: Topiramate
Use: Migraine Prevention


My husband suffers from chronic migraines and had a bad reaction to this medicine. We were very surprised to read this information on fertility as he was given this medicine to take as we are in the midst of trying for another baby. Thankfully we found this information before he could take this medicine more than a day or so.

This is a drug one that couples hoping to conceive should avoid, if possible. For females: It may cause birth defects in babies for expecting mothers taking this drug. For males:  A study was done on male rats who ingested 100 mg of Topiramate in 60 days. The male rats had decrease weight in reproductive organs and the number of female rats impregnated by male rats on long term Topiramate diet had decreased. The number of implantation and viable pregnancies from females impregnated by male rats on long term Topiramate diets decreased. Link to study: http://www.ncbi.nlm.nih.gov/pubmed/15580169

Citation
Otoom S, Batieneh H, Hassan Z, Daoud A. "Result Filters." National Center for Biotechnology Information. U.S. National Library of Medicine, 25 Oct. 2004. Web. 26 Oct. 2014. <http://www.ncbi.nlm.nih.gov/pubmed/15580169>.



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